Black female patients with systemic lupus erythematosus who face racial discrimination may be at a greater risk of experiencing higher levels of inflammation, according to a new study published by Martz et al in the journal Brain, Behavior, and Immunity. Investigators examined self-reported incidents of racial discrimination as well as C-reactive protein levels of 380 patients enrolled in the BeWELL Study from April 2015 to May 2017. After a follow-up of 2 years, the investigators discovered that incidents of racial discrimination were correlated with elevated C-reactive protein levels—for each domain of discrimination experienced, these levels increased by 3.98%. The investigators emphasized that racial discrimination may pose a significant health threat to Black female patients and that their new findings represent a need to eliminate racial inequities to improve the quality of life of this patient population. In a companion press release from Ochsner Health System, the study authors concluded that: “Understanding how racial discrimination compromises health and inflammatory pathways is crucial in our pursuit of more equitable and just [patient] outcomes.”
August 24, 2023