According to an article published in Dermatology Times, experts recommended using individualized treatment plans to treat acne vulgaris during pregnancy and lactation. In a literature review published by Ly et al in Dermatology and Therapy, investigators explained that several commonly prescribed treatments are contraindicated during pregnancy and lactation as a result of their systemic effects. However, some topical and oral medications may not have maternal or fetal risks. Topical treatments containing azelaic acid and benzoyl peroxide are currently considered safe and effective for use during pregnancy and lactation. Other topical treatments such as clindamycin and erythromycin may be used to reduce inflammation, as well as over-the-counter agents containing salicylic acid with concentrations lower than 2%. Oral medications such as penicillin and cephalexin have been found to be safe for short-term use during pregnancy and lactation; however, investigators warned against prolonged or excessive use. Further, certain procedural interventions, including intralesional corticosteroids in small quantities and light and laser therapies in low doses—alongside continued monitoring—may effectively treat acne cysts, inflammatory nodules, and refractory acne with minimal systemic absorption. The experts concluded that individualized treatment plans as well as patient education and counseling may be crucial for managing acne and should be backed by evidenced-based practices.


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