Nonmelanoma skin cancer may be responsible for a greater number of global deaths and may be underreported compared with melanoma, according to a press release from the European Academy of Dermatology and Venereology (EADV). These findings were presented by Salah et al at the EADV Congress 2023. Although nonmelanoma skin cancer may be less likely to be fatal than melanoma, it has been found to have a significantly higher incidence. Investigators used data from the World Health Organization International Agency for Research on Cancer to examine the global burden and associated outcomes of melanoma and nonmelanoma skin cancer cases. In 2020, there were nearly 1.2 million cases of nonmelanoma skin cancer across the world vs about 355,000 cases of melanoma. Fair-skinned and elderly patients from the United States, United Kingdom, France, Germany, Italy, and Australia had a high incidence of skin cancer; however, patients in Africa also experienced a high incidence and mortality from skin cancer. The investigators also identified specific populations that were potentially at a greater risk of developing nonmelanoma skin cancer—including individuals who worked outside, organ transplant recipients, and those with xeroderma pigmentosum. “There is an ongoing need to develop awareness campaigns that educate the general public about the risks of sun exposure and other relevant risk factors. These campaigns should be tailored to at-risk populations … [and] should also extend to populations that may not typically be considered … high risk, such as [individuals with darker skin tones]. Skin cancers are preventable and treatable, so we need to do more to ensure we are stopping the progression of this disease as early as possible to save lives,” concluded lead study author Thierry Passeron, MD, PhD, Professor and Chair of Dermatology as well as President of the Department of Clinical Research and Innovation at the Nice University Hospital.