Climate change–related environmental hazards may adversely impact atopic dermatitis, according to a report from HCPLive detailing a recent analysis. In a report published by Wang et al in Allergy, investigators used Embase, PubMed, and Google Scholar to analyze data from 18 studies that identified patients’ locations, ages, and outcomes as well as environmental triggers of atopic dermatitis—including toxins, ultraviolet radiation, temperature variations, allergens, and humidity. They explained that these triggers may be capable of causing inflammation, immune dysregulation, skin barrier impairment, cutaneous dysbiosis, and chronic itch. Further, the investigators compared global cumulative exposure data in 2005 and 2017 with prevalence shifts in atopic dermatitis and projected 2053 exposure. They suggested that climate change may directly result in increases in temperature-induced pruritis, proinflammatory cytokines, aeroallergens, psychological and physical stress provoked by extreme weather events and heat waves, and oxidative stress related to wildfires and poor air quality—thereby highlighting the potential for an exacerbated burden of atopic dermatitis. Additionally, events such as droughts, sea level rises, storms, flooding, and oceanic changes may all have indirect effects on the condition. The investigators developed past, present, and future comparative maps depicting the Cumulative Climate Hazard Index to help better understand and predict the effects of climatic issues on the prevalence of atopic dermatitis across the world. They found that Africa, Southeast Asia, and Central America faced the highest cumulative climatic hazards; and that by 2053, tropical and coastal regions may experience major impacts from these hazards. The investigators emphasized that if climate change continued in line with current trends, climatic hazards may rise significantly by 2053 (Cumulative Climate Hazard Index range = 0.24–4.18) compared with 2017 (Cumulative Climate Hazard Index range = 0.01–2.65). “Our study adds to the research on climate change by providing clarity about the extent of research on climatic hazards and [atopic dermatitis],” concluded the study authors.