A research letter published by Kahn et al in JAMA Network Open discovered multiple snares in the rollout of the JYNNEOS vaccine in the United States, including the distance of vaccine sites from a large chunk of the population; racial disparities in vaccine access; and a mismatch between the number of cases, vaccines shipped, and vaccine sites. The authors revealed that 47% of the U.S. population lived more than an hour away from the nearest mpox vaccination site; only smaller states and areas—specifically, Connecticut, Rhode Island, and Washington, DC—were able to ensure their entire populations had reasonable geographic access to a vaccine site. Racial disparities were also noted in access—over 46% of White individuals in the U.S. lived within 30 minutes of an mpox vaccination site, vs 16.3% of Black individuals and 30% of Hispanic individuals. In a companion press release on the findings from Yale University, lead study author Peter A. Kahn, MD, MPH, ThM, noted, “The correlation between vaccine distribution and cases suggests the public health infrastructure that responded to mpox was responsive and efficient…. But this rapid response exposed cracks in our health care delivery system; early access was not equal, with Black and Hispanic individuals lacking access.”