Over 50% of all melanoma diagnoses among White patients in the United States may in fact be overdiagnoses, according to a recent study published by Adamson et al in BMJ Evidence–Based Medicine. In the study, investigators found that in the United States, approximately 50% of melanoma diagnoses among White male patients and 65% of diagnoses among White female patients were cases of overdiagnosis in 2018—totaling 83,000 cases of melanoma. After analyzing national data, the investigators discovered that the lifetime risk of being overdiagnosed with melanoma increased from 1975 to 2018. Additionally, a large proportion of the overdiagnoses were stage 0 melanoma. The investigators estimated that 89% and 85% of these melanoma cases may be overdiagnosed in White male and female patients in the United States, respectively. The study authors concluded, “Melanoma overdiagnosis among White Americans is significant and increasing over time with an estimated 44,000 overdiagnosed in men and 39,000 in women in 2018. A large proportion of overdiagnosed melanomas are in situ cancers, pointing to a potential focus for intervention.”


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